Peptide health foods only need to be placed in a cool, dry place.
For peptide reagents and peptide drugs, they need to be stored in a desiccat. Freeze-dried peptides can be left at room temperature before exposing them to air. This will be a reduction in humidity effects, and when freeze-drying is not possible, the best way is to store in small working sample volumes. For peptide reagents containing Cys, Met or TrP, the deoxidation buffer is essential for their solubilization, because the peptide reagents are easily oxidized by air, and the slow flow of nitrogen or argon from the peptide reagents before sealing the bottle will also reduce the oxidation effect. Peptide reagents containing Gln or Asn are also susceptible to degradation, all of which have a limited lifetime compared to those that do not contain these problematic glycosides.
Peptides have a wide range of solubility. The main problem with peptide insolubility is the formation of secondary structures. This happens with all but the most superphosphate peptides, especially in peptides with multiple hydrophobic residues. Salt promotes the formation of secondary structures. We recommend dissolving the peptide in sterile distilled water or deionization first. If it is necessary to increase the solubility rate, sonication can be used. If there is still a problem with dissolving, add a small amount of dilute acetic acid (10%) or ammonia, which will be easy to dissolve.
For long-term storage of peptide reagents, it is best to freeze-dry, and cold-dried powders can be stored at -20°C or lower for several years with little or no degradation. The polypeptides in solution are far from stable. Peptides are susceptible to bacterial degradation and should be dissolved in sterile purified water.
Peptide solutions containing Met, Cys, or Tyr residues have a limited lifespan due to oxidation. It should be dissolved in oxygen-free solvent, in order to prevent the destruction of repeated freeze-thaw cycles, it is recommended to dissolve excess peptides in a stool experiment, and the rest of the peptides should be stored in solid formation.
